https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42662 Wed 31 Aug 2022 13:51:25 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43693 M = 76.1 g, SD = 17.0) than impacts that did not result in a concussion (M = 34.2g, SD = 18.0; Cohen’s d = 2.4). Conclusions: The vast majority (94%) of impacts ≥ 20 g captured by the x-patch™ sensor were video verified in semi-professional rugby league games. The use of a secondary source of information to verify impact events recorded by wearable sensors is beneficial in clarifying game events and exposure levels.]]> Wed 28 Sep 2022 09:34:05 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50288 Wed 28 Feb 2024 16:40:22 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:53567 Wed 28 Feb 2024 16:32:39 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47741 Wed 25 Jan 2023 15:21:43 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30085 Wed 24 Nov 2021 15:50:06 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18338 Wed 24 Jun 2015 11:36:33 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51178 Wed 24 Apr 2024 12:15:17 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30321 Wed 16 May 2018 13:39:09 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48359 Wed 15 Mar 2023 11:41:52 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44378 n = 12) aged 18–35 years completed two fMRI scans (fasted and fed) while viewing high-calorie food images and low-calorie food images. Food addiction symptoms were assessed using the Yale Food Addiction Scale. Associations between FA symptoms and activation of the BLA and central amygdala were tested using bilateral masks and small-volume correction procedures in multiple regression models, controlling for BMI. Participants were 24.1 ± 2.6 years, with mean BMI of 27.4 ± 5.0 kg/m2 and FA symptom score of 4.1 ± 2.2. A significant positive association was identified between FA symptoms and higher activation of the left BLA to high-calorie versus low-calorie foods in the fasted session, but not the fed session. There were no significant associations with the central amygdala in either session. This exploratory study provides pilot data to inform future studies investigating the neural mechanisms underlying FA.]]> Wed 12 Oct 2022 11:14:14 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:13783 Wed 11 Apr 2018 16:00:09 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:16960 Wed 11 Apr 2018 12:30:27 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21275 in vivo brain magnetic resonance spectroscopy biomarkers is investigated with respect to parameter values for two key stages of post-acquisitional processing. Our effort is specifically motivated by the lack of consensus on approaches and parameter values for the two critical operations, water resonance removal, and baseline correction. The different stages of data processing also introduce varying levels of uncertainty and arbitrary selection of parameter values can significantly underutilize the intrinsic differences between two classes of signals. The sensitivity of biomarkers points to the need for a better understanding of how all stages of post-acquisitional processing affect biomarker discovery and ultimately, clinical translation. Our results also highlight the possibility of optimizing biomarker discovery by the careful selection of parameters that best reveal class differences. Using previously reported data and biomarkers, our results demonstrate that small changes in parameter values affect the statistical significance and corresponding effect size of biomarkers. Consequently, it is possible to increase the strength of biomarkers by selecting optimal parameter values in different spectral intervals. Our analyses with a previously reported data set demonstrate an increase in effect sizes for wavelet-based biomarkers of up to 36%, with increases in classification performance of up to 12%.]]> Wed 11 Apr 2018 12:19:42 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27129 in-vivo measurement of brain biochemistry. The objective of this study was to explore the effects of a commercial energy drink (ED) on brain metabolites in adult males using MRS. Methods: Ten males (18 to 30 years), of mean body mass index 23.8±2.2 kg/m² [range 21.4-27.8 kg/m²] were recruited and randomized to either the intervention group (n=5) or control group (n=5). The intervention group were asked to consume two 250ml cans of Red Bull and the control group consumed no drink. One dimensional MRS on a 1.5T Achieva MRI scanner was obtained of bi-occipital gray matter. Subjects were placed in the scanner and a spectrum acquired every 5.75 minutes for 60 minutes. Linear mixed models were generated to determine the main effects due to differences between groups and times and the interaction. Results: There was a significant group by time effect for N-acetylaspartate (NAA) (P= .02, d= 0.7) and a statistical trend for macromolecule 20 (MM20) (P= .06 d= 0.1) with the control group having higher concentrations than that of the intervention. Mean differences from baseline to 45 minutes for NAA in the intervention group were -0.8 mM (-12%) compared with 0.15 mM (<1%) for control and for MM20 -0.12 mM (<1%) in the intervention group compared with 0.03 mM (<1%) for control. Conclusions: Consumption of two cans of ED was found to produce few changes in brain metabolites with moderate effect sizes. Changes detected in this study demonstrate the sensitivity of the MRS method to explore nutrition related variables with 1.5T clinical MRI unit. The study provides some insight into an understudied, topical area of research.]]> Wed 11 Apr 2018 12:09:41 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:9164 Wed 11 Apr 2018 11:29:56 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14529 18 years old, reported weight status, and included fMRI outcomes. Sixty studies were identified that investigated the neural responses of healthy weight participants (n = 26), healthy weight compared to obese participants (n = 17), and weight-loss interventions (n = 12). High-calorie food images were used in the majority of studies (n = 36), however, image selection justification was only provided in 19 studies. Obese individuals had increased activation of reward-related brain areas including the insula and orbitofrontal cortex in response to visual food cues compared to healthy weight individuals, and this was particularly evident in response to energy dense cues. Additionally, obese individuals were more responsive to food images when satiated. Meta-analysis of changes in neural activation post-weight loss revealed small areas of convergence across studies in brain areas related to emotion, memory, and learning, including the cingulate gyrus, lentiform nucleus, and precuneus. Differential activation patterns to visual food cues were observed between obese, healthy weight, and weight-loss populations. Future studies require standardization of nutrition variables and fMRI outcomes to enable more direct comparisons between studies.]]> Wed 11 Apr 2018 10:57:34 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28129 3. The external body deformation caused a mean dose reduction of 0.6 ± 0.3 Gy, while the coverage reduced by 22% ± 13% and 27% ± 6% in V₉₈ and V₁₀₀, respectively. A dedicated MR simulation setup for prostate radiotherapy is essential to ensure the agreement between planning anatomy and treatment anatomy. The image signal was reduced after applying the coil mount, but no significant effect was found on prostate contouring.]]> Wed 11 Apr 2018 09:52:08 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32689 Wed 10 Nov 2021 15:04:19 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:28370 Wed 06 Apr 2022 13:59:43 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32816 Wed 02 Mar 2022 14:28:29 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42438 Tue 23 Aug 2022 10:26:29 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:17800 Tue 22 Aug 2023 16:16:47 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43320 Tue 21 Mar 2023 18:41:26 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48063 fed") change in resting-state functional connectivity of the ventral and dorsal striatum, and its association with FA scores (controlling for BMI). Results: Higher symptoms of FA correlated with greater changes in ventral caudate-hippocampus connectivity between fasted and fed conditions. FA symptoms did not correlate with connectivity in the dorsal caudate circuit. Post-hoc analyses revealed that participants with higher symptoms of FA had ventral caudate-hippocampus hyperconnectivity in the fasted scan only, as well as a significant reduction of this connectivity between the fasted and fed scans. Conclusions: Heightened connectivity in the ventral striatum during a fasted state, which has been linked to reward prediction signals, underpins symptoms of FA. In contrast, connectivity in the dorsal striatum or "habit" system is unrelated to homeostatic status and FA symptoms, and is thus less relevant for subclinical manifestations of FA.]]> Tue 21 Feb 2023 12:23:55 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43477 p < .001) and had significantly worse delayed recall of a visually complex design (p = .04). They did not differ from controls on other clinical outcome measures. There were no differences in cortical thickness between the groups. Professional players had smaller whole brain (p = .003), bilateral hippocampi (ps = .03), and left amygdala volumes (p = .01) compared to healthy controls. Within the players group, there were significant associations between greater alcohol use and smaller bilateral hippocampi and left amygdala volumes. There were no associations between structural volumes and history of concussions or memory performance. Conclusions: The literature examining cortical thickness in athletes with a history of multiple concussions is mixed. We did not observe differences in cortical thickness in professional rugby league players compared to controls. However, smaller subcortical volumes were found in players that were, in part, associated with greater alcohol consumption.]]> Tue 20 Sep 2022 10:48:22 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48296 Tue 14 Mar 2023 12:07:36 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43132 Tue 13 Sep 2022 15:07:23 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32339 Thu 24 May 2018 10:50:05 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39028 n = 11) with a history of multiple self-reported concussions compared with age- and education-matched controls (n = 13) who have had no history of brain trauma. Diffusion-weighted images were acquired with a Siemens 3T scanner. All participants completed a clinical interview. There were no significant differences between groups on measures of depression, anxiety, stress, or post-concussion symptoms; however, NRL players scored significantly higher on the alcohol use disorder identification test (AUDIT). Voxelwise analyses of DTI measures were performed using tract-based spatial statistics (TBSS) with age and AUDIT scores included as covariates. TBSS revealed significantly reduced fractional anisotropy (FA), and increased radial diffusivity (RD), axial diffusivity (AD), and trace (TR) in white matter regions of recently retired NRL players compared with controls. FA was significantly reduced in the right superior longitudinal fasciculus and right corticospinal tract while TR, RD, and AD were increased in these regions, as well as the corpus callosum, forceps major, right uncinate fasciculus, and left corticospinal tract. In summary, DTI in a small cohort of recently retired professional NRL players with a history of multiple concussions showed differences in white matter microstructure compared with age- and education-matched controls with no history of brain trauma.]]> Thu 21 Apr 2022 15:32:34 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18914 35 years, females, and overweight/obese participants. Additionally, YFAS diagnosis and symptom score was higher in clinical samples compared to non-clinical counterparts. YFAS outcomes were related to a range of other eating behavior measures and anthropometrics. Further research is required to explore YFAS outcomes across a broader spectrum of ages, other types of eating disorders and in conjunction with weight loss interventions to confirm the efficacy of the tool to assess for the presence of FA.]]> Thu 20 Sep 2018 15:13:00 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:17340 Thu 20 Sep 2018 15:06:33 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46388 Thu 17 Nov 2022 14:11:47 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29940 Thu 04 Nov 2021 10:39:20 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29967 Thu 03 Feb 2022 12:22:05 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:13275 Sat 24 Mar 2018 08:15:16 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20840 Sat 24 Mar 2018 08:05:57 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20363 Sat 24 Mar 2018 07:58:13 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21170 ®, MEDLINE^®, EMBASE, SPORTDiscus™, Scopus, Web of Science, and Informit; using the key search terms: diffusion tensor imaging, diffusion magnetic resonance imaging, diffusion weighted MRI, diffusion MRI, fractional anisotropy, tractography, apparent diffusion coefficient, magnetic resonance imaging, mild traumatic brain injury, mTBI, traumatic brain injury, concussion, sport, athletic and athlete. Observational, cohort, correlation, cross-sectional and longitudinal studies were all included in the current review. Results of the review found eight articles that met inclusion criteria, which included data on 214 athletes and 96 controls. Seven of eight studies reported some type of DTI abnormality, although the neuroanatomical sites involved varied. Although considerable methodological variations exist across studies, the current review suggests that DTI may possess adequate diagnostic sensitivity to detect SRC in affected athletes. Further longitudinal studies are required to demonstrate its discriminate validity and prognostic capacity within this field.]]> Sat 24 Mar 2018 07:58:05 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21251 Sat 24 Mar 2018 07:54:34 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21327 Sat 24 Mar 2018 07:52:51 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20124 Sat 24 Mar 2018 07:51:45 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26150 Sat 24 Mar 2018 07:35:26 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26953 Sat 24 Mar 2018 07:27:03 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26978 Sat 24 Mar 2018 07:26:58 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27598 Sat 24 Mar 2018 07:25:17 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27596 Sat 24 Mar 2018 07:25:16 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22298 Sat 24 Mar 2018 07:17:29 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:23590 Sat 24 Mar 2018 07:13:22 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24660 Sat 24 Mar 2018 07:11:51 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25019 Sat 24 Mar 2018 07:10:41 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48688 Mon 27 Mar 2023 15:56:46 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32690 Mon 23 Sep 2019 13:22:20 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42376 Mon 22 Aug 2022 14:29:29 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52810  3 months and age- and sex-matched asymptomatic controls, muscle volumes of levator scapulae, multifidus including semispinalis cervicis (MFSS), semispinalis capitis, splenius capitis including splenius cervicis (SCSC), sternocleidomastoid and longus colli from C3 through T1 were quantified from magnetic resonance imaging. Between-group differences were determined using linear mixed models, accounting for side (left or right), muscle, spinal level, sex, age, and body mass index (BMI). Individuals with pain had greater muscle volume (mean difference 76.8mm3; 95% CI 26.6–127.0; p = .003) and MFI (2.3%; 0.2–4.5; p = .034) of the MFSS compared to matched controls with no differences in relative volume, accounting for factors associated with the outcomes: muscle, spinal level, side (left had smaller volume, relative volume and MFI than right), sex (females had less volume and relative volume than males), age (older age associated with less relative volume and greater MFI), and BMI (higher BMI associated with greater muscle volume and MFI). Greater MFI in individuals with chronic idiopathic neck pain suggests a possible underlying mechanism contributing to neck pain. Perspective: These findings suggest MFI in the MFSS may be radiologic sign, potentially identifying patients with a less favourable prognosis. Future studies are needed to confirm this finding and determine if MFI is a contributor to the development or persistence of neck pain, or consequence of neck pain.]]> Fri 27 Oct 2023 15:44:23 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42273 Fri 19 Aug 2022 14:44:32 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48912 20, and (e) qualitative or quantitative assessment of pre-intervention collateral status on imaging using a grading scale. Random-effects meta-analysis was performed to investigate the association of aetiology with pre-intervention collateral status, and forest plots of risk ratio (RR) were generated. Results: A meta-analysis was conducted on seven studies, with a cumulative cohort of 1235 patients, to assess the association of pre-intervention collateral status with stroke aetiology. Patients with LAA were associated significantly with an increased rate of good collaterals (RR 1.24; 95% CI 1.04–1.50; p = 0.020, z = 2.33). Contrarily, CE aetiology was associated significantly with a decreased rate of good collaterals (RR 0.83; 95% CI 0.71–0.98; p = 0.027, z = −2.213). Conclusions: This study demonstrates that, in AIS patients receiving reperfusion therapy, LAA and CE aetiologies are associated significantly with collateral status.]]> Fri 14 Apr 2023 18:25:59 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38429 p = 0.04, ROC AUC 0.90) and standard deviation (SD) (p = 0.02, ROC AUC 0.90), week 2 skewness (p = 0.02, ROC AUC 0.91) and SD (p = 0.01, ROC AUC 0.94), week 4 kurtosis (p = 0.01, AUC 0.92) and SD (p = 0.01, ROC AUC 0.96). Changes in minimum ADC between baseline and week 2 (p = 0.02, ROC AUC 0.94) and baseline and week 4 (p = 0.02, ROC AUC 0.94) were prognostic for local recurrence. For prediction of any recurrence, ADC minimum (p = 0.02, ROC AUC 0.87) and SD (p = 0.01, ROC AUC 0.85) at baseline, and ADC maximum (p = 0.03, ROC AUC 0.77) and SD (p = 0.02, ROC AUC 0.81) at week 4 were significant. On LASSO logistic regression, ADC minimum and SD at baseline were retained for any recurrence. The only significant finding for DCE-MRI was a correlation of k-trans min at the second follow-up with local recurrence (p = 0.05, AUC 0.84). Conclusion: Several ADC parameters at various time points correlate with recurrence suggesting DW-MRI is a potential biomarker for SCCAC.]]> Fri 10 Sep 2021 12:16:47 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39976 controls group contrast. Post hoc seed-to-voxel analyses using the MVPA cluster results as seeds were performed to characterize functional connectivity abnormalities from brain regions identified by MVPA. MVPA revealed one cluster of abnormal functional connectivity located in cerebellar lobule V. This region of lobule V corresponded to the ventral attention network. Post hoc seed-to-voxel analysis using the cerebellar MVPA cluster as a seed revealed multiple areas of cerebral cortical hyper-connectivity and hypo-connectivity in retired athletes when compared with controls. This initial report suggests that cerebellar dysfunction might be present and clinically important in some retired athletes.]]> Fri 01 Jul 2022 09:51:32 AEST ]]>